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We review the role of renal fibrosis in feline CKD. Abstract Chronic kidney disease CKD is a common medical condition of ageing cats. In most cases the underlying aetiology is unknown, but the most frequently reported pathological diagnosis is renal tubulointerstitial fibrosis. Renal fibrosis, characterised by extensive accumulation of extra-cellular matrix within the interstitium, is thought to be the final common pathway for all kidney diseases and is the pathological lesion best correlated with function in both humans and cats. As a convergent pathway, renal fibrosis provides an ideal target for the treatment of CKD and knowledge of the underlying fibrotic process is essential for the future development of novel therapies. There are many mediators and mechanisms of renal fibrosis reported in the literature, of which only a few have been investigated in the cat.

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Anyone who knows their way around Renpy? I kinda need a calender system in my game monday to sunday, also counting months. If you are just displaying the current day, but want a date system, take a look at Lab Rats the first one. It’s been a while, but I did some personal tweaking under the hood there, and it had not only a day system, but also had multiple time periods for each day.

Where do you hood rats come from. What filthy potty mouths you people are. Can any of you people carry yourselves with a little class, let alone speak like you have some class and intelligence!

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As the third Robin in the Batman comics, he served as Batman ‘s sidekick, and he is a superhero in his own right. He currently uses the superhero identity of Red Robin. Contents History Tim Drake the 3rd Robin Tim Drake was little more than a toddler when he attended the circus with his parents. In order to ease his wife’s concerns that the circus might frighten Tim, Jack Drake asked to take a picture with the Flying Graysons, who were the starring act. It was here that Tim first met Dick Grayson , who offered Tim special attention, and even promised to dedicate his performance to the toddler.

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She is a senior at Hamilton Hill High. She has been dating Terry Mcginnis off and on for several years. She is often annoyed by his many disappearing acts. Dana at one time, was being terrorized by a disfigured stalker named Patrick Fitz who others referred to as Ratboy. Terry saved Dana from Patrick and his vermin minions but Terry had inadvertly caused an explosion which scarred Patrick even more.

A few weeks had passed since Dana’s encounter with Patrick in the sewers but she still had not gotten over the fear of being attacked by rats.

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Hood Rats by C’Moore Productions most black men find it easier to settle for a hood rat because While the hood rats are at the grocery store with their borrowed Vision card. Real women are in college, into their careers, or on their jobs working hard.

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Our Story A little bit about us.. Kathy and Jonny met at the Air Force Academy and were assigned to the same basic squadron. This meant that after going through basic cadet training together, they were in the same squadron for the first two years of the Academy. But they did not really get to know each other until the second semester of freshman year when they sat next to each other in a 7: Jonny, being a morning person, would always make sure to keep Kathy awake in this class.

They quickly became the best of friends and remained best friends all throughout college. They never really thought of the other as more than a friend and if you had told them freshman or sophomore year that they would get married, they would have both laughed true story. But God had something different planned for them and entering senior year, they decided to take a leap of faith and began dating which, in hindsight, was probably the best decision they ever made.

They graduated from the Academy in June and spent that summer travelling the world with their two best friends. They are looking forward to finally living together in Minot, North Dakota this summer!

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We all know a few. Some of them work down at your local hospital, sticking you with needles and processing you in and out of the healthcare system. What am I referring to? A glorified hoodrat is the female you run across online on one of the popular dating sites. Glorified hoodrats typically work at average jobs that come with a few health benefits, live in average neighborhoods most likely an apartment complex , drive an average vehicle and typically does average things in their spare time.

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So part of drug dealing is, believe it or not, educating people as to how to use drugs safely and responsibly — you don’t want your clients to overdose because that’s bad for business, and also because drug dealers aren’t all cartoonish monsters with no souls. That shit’ll cost you another bill, maybe two. I offered him some weed, and he acted like I was trying to kill his family with a spoon. I spent 45 minutes, maybe an hour, explaining to him how wrong that was.

I’m not giving a sophomore that cocaine. Kid’s like 5 feet 2 inches, pounds. Weed may be as harmless as a garter snake whose heart is filled with love, but meth is more like a king cobra whose venom sacs are filled with meth. Please don’t buy meth! Smoking rock candy is a great way to gain all the social benefits of meth use with none of the open sores. Continue Reading Below Continue Reading Below Advertisement No, we didn’t go looking for a drug dealer at the stupidest high school in the country — according to studies, this is exactly the effect anti-drug campaigns have had on youth.

One of the biggest impacts of the s anti-drug PSAs was actually to convince kids all their friends were smoking pot. When C’s husband got busted, it was like being on the receiving end of a full Die Hard. The times he wasn’t there it was only three or four officers,” she says, describing the time when her husband was on the lam.

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Pin it Dear Matt A: Have you ever heard of rats chewing the wiring in a car engine? Rats are eating my car! What I’m wondering is, why are they doing it and how can I stop them? I had a rodent problem. What’s the real hocus pocus? Is there an effect on little human minds? Rats’ teeth grow constantly. Rule of the Universe 2: To wear down their teeth, rats chew on absolutely anything. It’s very common for them to seek warmth and protection in an engine compartment and gnaw away wires, belts, hoses, whatever happens to be lying around.

If the car’s not driven frequently, they might even nest in your dashboard, your trunk, under your seats.

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Share via Email This article is over 3 months old Issa Rae, the creator and star of Insecure, which has appealed to a multiracial audience. Insecure has already won the actor-writer-director a Peabody award , while Golden Globe and Emmy nominations have rolled in for the show. To say that she is having a moment might be something of an understatement. The show went viral on Facebook and propelled her to create Awkward Black Girl which then became a cult phenomenon, picking up millions of viewers on YouTube in In it, she depicted the daily inanity of office life, the humdrum of millennial anxiety and the ups and downs of dating in LA — an otherwise unremarkable and universal set-up — except that the central cast were black.

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How The Course Works The Rationale Of The Course Learning to write in a style is learning an activity – like playing the violin, sprinting, pole-vaulting, sparring, riding a horse. This course and the book that grew out of it teach an activity, not a content. Students consider the concept of style and learn to notice style, to recognize styles, and to analyze styles.

Analyzing them makes it much easier to acquire them. A style consists of a conceptual stand on some basic intellectual questions that are the elements of style. Learning to write in a style is learning to inhabit its conceptual stand. We select one style, classic style, for daily practice. Classic style is a general style, suitable for presenting anything, accessible to anyone who wishes to learn it.

Although there are many distinguished classic writers who work in English, and although workaday classic style is widely used in journalism, advertising, and instruction in English, classic style is not a routine style in the English-speaking world and is almost never taught in its schools. This unfamiliarity with writing in classic style actually makes it easier for the student to recognize that classic style is a style, to detect the classic stand, and to practice classic style without sliding into intuitive and unconscious but poorly developed or incoherent former versions of it.

Signs You’re Dating a Hood Dude